Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem Fab) (BSFAB-H241)

Recombinant Anti-CD3 x Anti-CD4 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-CD3 and anti-CD4 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget T cells to HIV-1 infected cells. It is designed for the research of HIV-1 infection, AIDS therapy.

Datasheet

Specifications

Targets

CD3 & CD4

Type

Tandem Fab

Species Reactivity

Human

Target 1

CD3

Host Animal 1

Human

Target 2

CD4

Host Animal 2

Human

Application

FuncS; Promising therapeutic agent

Related Disease

HIV-1 infection, AIDS

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

CD4

Gene ID

920

UniProt ID

B4DT49

Alternative Names

CD4; CD4 molecule; CD4mut; T-cell surface glycoprotein CD4; CD4 receptor; CD4 antigen (p55); T-cell surface antigen T4/Leu-3

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