Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (scFv-CH3) (BSFC-071)

Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD3 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CD8 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget T cells to HIV infected cells. It is designed for the research of HIV-1 infection, AIDS therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & CD8

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

HIV-1 infection, AIDS

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

CD8

Gene ID

925

UniProt ID

P01732

Alternative Names

CD8A; CD8a molecule; Cluster of differentiation 8; CD8; MAL; p32; Leu2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (scFv-CH3) (BSFC-071). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-CD3 x Anti-CD8 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-071)

Specifications

Targets

Customer Reviews and Q&As