Home > Products > CD3 & CEA > Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (Miniantibody)

Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (Miniantibody)  (MNAB-H248)

Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-CD3 antibody variable domain is linked to another scFv of an anti-CEA antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can retarget T cells to tumor cells. It is designed for the research of Colorectal cancer (CRC); Breast cancer; Lung cancer; Gastric cancer therapy.

Specifications
Targets
CD3 & CEA
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Mouse
Target 2
CEA
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Colorectal cancer (CRC); Breast cancer; Lung cancer; Gastric cancer
Targets
Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; Carcinoembryonic antigen; CD66e; meconium antigen 100

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