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Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (scDiabody-CH3)  (CAT#: SCDBC-072)

Recombinant Anti-CD3 x Anti-CEA Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD3/anti-CEA diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can retarget T cells to tumor cells. It is designed for the research of Colorectal cancer (CRC); Breast cancer; Lung cancer; Gastric cancer therapy.
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Specifications

Targets
CD3 & CEA
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Colorectal cancer (CRC); Breast cancer; Lung cancer; Gastric cancer

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen-related cell adhesion molecule 5; CEA; Carcinoembryonic antigen; CD66e; meconium antigen 100
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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