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Recombinant Anti-CD3 x Anti-CLEC12A Bispecific Antibody (Minibody) (CAT#: MiniB-073)
Recombinant Anti-CD3 x Anti-CLEC12A Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD3 scFv fused to N-terminus of Knob-CH3 domain and the anti-CLEC12A scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can retarget T cells to tumor cells. It is designed for the research of Acute myeloid leukemia (AML); Myelodysplastic syndromes (MDS); Chronic myelogenous leukemia (CML) therapy.
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