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Recombinant Human Anti-CD3 x Anti-DLL3 Bispecific Antibody (IgG-scFv)  (CAT#: IGFV-H250)

Recombinant Anti-CD3 x Anti-DLL3 Bispecific Antibody (IgG-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Lung cancer; Pancreatic cancer; Skin cancer; Solid tumors therapy.
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Specifications

Targets
CD3 & DLL3
Type
IgG-scFv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Lung cancer; Pancreatic cancer; Skin cancerSolid tumors

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
DLL3
Gene ID
UniProt ID
Alternative Names
DLL3; delta-like 3 (Drosophila); Delta-like 3; SCDO1; delta-like protein 3; delta3; drosophila Delta homolog 3; Delta like canonical notch ligand 3
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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