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Recombinant Anti-CD3 x Anti-DLL3 Bispecific Antibody (scDiabody-CH3)  (CAT#: SCDBC-076)

Recombinant Anti-CD3 x Anti-DLL3 Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD3/anti-DLL3 diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can retarget T cells to tumor cells. It is designed for the research of Lung cancer; Pancreatic cancer; Skin cancer; Solid tumors therapy.
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Specifications

Targets
CD3 & DLL3
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Lung cancer; Pancreatic cancer; Skin cancer; Solid tumors

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
DLL3
Gene ID
UniProt ID
Alternative Names
DLL3; delta-like 3 (Drosophila); Delta-like 3; SCDO1; delta-like protein 3; delta3; drosophila Delta homolog 3; Delta like canonical notch ligand 3
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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