Home > Products > CD3 & EPCAM > Recombinant Anti-CD3 x Anti-EPCAM Bispecific Antibody (TandAb)

Recombinant Anti-CD3 x Anti-EPCAM Bispecific Antibody (TandAb)  (TANDAB-H253)

Recombinant Anti-CD3 x Anti-EPCAM Bispecific Antibody (TandAb) is designed to be expressed as a monomeric subunit (single chain Diabody, scDb), with four variable domains from two parental antibodies. Then the two peptide chains can dimerize in a head-to-tail fashion. This BsAb can retarget T cells to tumor cells. It is designed for the research of Solid tumors therapy.

Datasheet
Specifications
Targets
CD3 & EPCAM
Type
TandAb
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Human
Target 2
EPCAM
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors
Targets
Target 1
CD3
Gene ID
916
UniProt ID
P07766
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
EPCAM
Gene ID
4072
UniProt ID
P16422
Alternative Names
EPCAM; epithelial cell adhesion molecule; ESA; KSA; M4S1; MK-1; DIAR5; EGP-2; EGP40; KS1/4; MIC18; TROP1; EGP314; HNPCC8; TACSTD1; epithelial glycoprotein 314; human epithelial glycoprotein-2; cell surface glycoprotein Trop-1; adenocarcinoma-associated antigen; tumor-associated calcium signal transducer 1; major gastrointestinal tumor-associated protein GA733-2; membrane component, chromosome 4, surface marker (35kD glycoprotein)
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