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Recombinant Human Anti-CD3 x Anti-FcRH5 Bispecific Antibody (Tandem Fab)  (CAT#: BSFAB-H255)

Recombinant Anti-CD3 x Anti-FcRH5 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-CD3 and anti-FcRH5 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget T cells to tumor cells. It is designed for the research of Multiple myeloma (MM); B cell malignancies therapy.
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Specifications

Targets
CD3 & FcRH5
Type
Tandem Fab
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Multiple myeloma (MM) B cell malignancies

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
FcRH5
Gene ID
UniProt ID
Alternative Names
FCRL5; Fc receptor like 5; CD307; FCRH5; IRTA2; BXMAS1; CD307e; PRO820
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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