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Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (IgG-Fv)  (CAT#: BSGV-083)

Recombinant Anti-CD3 x Anti-GD2 Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-CD3 antibody variable domain is fused to the C terminal of an IgG of anti-GD2 antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can retarget T cells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.
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Specifications

Targets
CD3 & GD2
Type
IgG-Fv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
GD2
Alternative Names
Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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