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Recombinant Human Anti-CD3 x Anti-GPC3 Bispecific Antibody (IgG-scFv)  (CAT#: IGFV-H261)

Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (IgG-scFv) is designed to be expressed as a LC and an extended HC with scFv moiety linked to the C terminus. It is a symmetric bispecific and tetravalent molecule, bivalent for each antigen specificity, 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Hepatocellular cancer (HCC); Melanoma therapy.
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Specifications

Targets
CD3 & GPC3
Type
IgG-scFv
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Hepatocellular cancer (HCC)Melanoma

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
GPC3
Gene ID
UniProt ID
Alternative Names
SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; GPC3; glypican 3
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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