Name: Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (sdAb-Fc-sdAb)
SKU: HCAB-026
Rating: 5 (1 reviews)

Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (sdAb-Fc-sdAb, Tetravalent Heavy Chain-only Antibody, Tetravalent HCAb) is symmetric protein with two pairs of single domain antibodies (sdAb), from anti-CD3 and anti-GPC3 antibodies, fused to the N-terminus and C-terminus of the Fc separately. This BsAb is bispecific, tetravelant, 2+2 antigen-binding valency. It can retarget T cells to tumor cells. It is designed for the research of Hepatocellular cancer (HCC); Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & GPC3

Type

sdAb-Fc-sdAb

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC); Melanoma

Host Animal 1

llama

Host Animal 2

llama

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

GPC3

Gene ID

93695

UniProt ID

Q99P91

Alternative Names

GPNMB; glycoprotein (transmembrane) nmb; ipd; Dchil; DC-HIL; transmembrane glycoprotein NMB; osteoactivin; iris pigment dispersion; dendritic cell-associated transmembrane protein; dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand; Glycoprotein non-metastatic b

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (sdAb-Fc-sdAb) (CAT#: HCAB-026)

Specifications

Targets

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