Name: Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (sdAb-IgG)
SKU: BSSG-381
Rating: 5 (1 reviews)

Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (sdAb-IgG) is formed by an IgG and two single domains antibodies (sdAbs). The sdAbs from an anti-GPC3 antibody variable domain are respectively connected to the N terminus of the anti-CD3 IgG heavy chains or light chains to form sdAb-(H)IgG or sdAb-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Hepatocellular cancer (HCC); Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & GPC3

Type

sdAb-IgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC); Melanoma

Host Animal 1

Mouse

Host Animal 2

llama

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

GPC3

Gene ID

2719

UniProt ID

P51654

Alternative Names

SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; GPC3; glypican 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (sdAb-IgG) (BSSG-381). Click the button below to contact us or submit your feedback about this product.

Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (sdAb-IgG) (CAT#: BSSG-381)

Specifications

Targets

Customer Reviews and Q&As