Recombinant Human Anti-CD3 x Anti-GPC3 Bispecific Antibody (Tandem Fab) (BSFAB-H261)

Recombinant Anti-CD3 x Anti-GPC3 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-CD3 and anti-GPC3 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget T cells to tumor cells. It is designed for the research of Hepatocellular cancer (HCC); Melanoma therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & GPC3

Type

Tandem Fab

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hepatocellular cancer (HCC)Melanoma

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

GPC3

Gene ID

2719

UniProt ID

P51654

Alternative Names

SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; GPC3; glypican 3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD3 x Anti-GPC3 Bispecific Antibody (Tandem Fab) (CAT#: BSFAB-H261)

Specifications

Targets

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