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Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-088)
Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-CD3 specificity or anti-GPNMB specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget T cells to tumor cells. It is designed for the research of Melanoma; Breast cancer therapy.
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