Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (scIgG) (SCIGG-088)

Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (scIgG) is designed to be expressed as two chains, each chain has the same units with their parental IgG antibodies, anti-CD3 and anti-GPNMB IgGs. The two chains form heterodimer via Fc KIH technology. This BsAb can retarget T cells to tumor cells. It is designed for the research of Melanoma; Breast cancer therapy.

Datasheet

Specifications

Targets

CD3 & GPNMB

Type

Single chain IgGs

Species Reactivity

Human

Target 1

CD3

Host Animal 1

Mouse

Target 2

GPNMB

Host Animal 2

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

Melanoma; Breast cancer

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

GPNMB

Gene ID

93695

UniProt ID

Q99P91

Alternative Names

GPNMB; glycoprotein (transmembrane) nmb; ipd; Dchil; DC-HIL; transmembrane glycoprotein NMB; osteoactivin; iris pigment dispersion; dendritic cell-associated transmembrane protein; dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand; Glycoprotein non-metastatic b

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY

Online Inquiry

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

UK
167-169 Great Portland Street, 5th Floor, London, W1W 5PE
Tel: 44-207-097-1828
Email: