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Recombinant Anti-CD3 VHH x Anti-HIV-1 gp120 VHH BispecificAntibody (Bi-sdAb)  (CAT#: BIVHH-024)

Recombinant Anti-CD3 x Anti-HIV-1 gp120 Bispecific Antibody (Bi-sdAb) is designed to be expressed as a VHH from anti-CD3 antibody variable domains fused with a VHH from an anti-HIV-1 gp120 antibody variable domains. It contains a His-tag at the C/N terminus for affinity purification. The BsAb exits as monomer in reducing and non-reducing conditions. This BsAb can retarget T cells to HIV-1 infected cells. It is designed for the research of HIV-1 infection, AIDS therapy.
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Specifications

Targets
CD3 & HIV-1 gp120
Type
Bi-sdAb
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
HIV-1 infection, AIDS

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
HIV-1 gp120
Gene ID
UniProt ID
Alternative Names
ENV; gp160; Envelope glycoprotein 120; envelope glycoprotein; Envelope surface glycoprotein gp160, precursor; hypothetical protein; Envelope surface glycoprotein gp120; Envelope transmembrane domain; human immunodeficiency virus type 1; human immunodeficiency virus type 1 gp120; human immunodeficiency virus type 1 glycoprotein 120; gp41; GP41; glycoprotein 41
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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