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Recombinant Anti-CD3 x Anti-HIV-1 gp41 Bispecific Antibody (sdAb-Fc-sdAb)  (CAT#: HCAB-025)

Recombinant Anti-CD3 x Anti-HIV-1 gp41 Bispecific Antibody (sdAb-Fc-sdAb, Tetravalent Heavy Chain-only Antibody, Tetravalent HCAb) is symmetric protein with two pairs of single domain antibodies (sdAb), from anti-CD3 and anti-HIV-1 gp41 antibodies, fused to the N-terminus and C-terminus of the Fc separately. This BsAb is bispecific, tetravelant, 2+2 antigen-binding valency. It can retarget T cells to HIV-1 infected cells. It is designed for the research of HIV-1 infection, AIDS therapy.
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Specifications

Targets
CD3 & HIV-1 gp41
Type
sdAb-Fc-sdAb
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
HIV-1 infection, AIDS
Host Animal 1
llama
Host Animal 2
llama

Targets

Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
HIV-1 gp41
Gene ID
UniProt ID
Alternative Names
SGB; DGSX; MXR7; SDYS; SGBS; OCI-5; SGBS1; GTR2-2; GPC3; glypican 3
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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