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Recombinant Anti-CD3 x Anti-IGF1R Bispecific Antibody (scFv-CH3) (CAT#: BSFC-092)
Recombinant Anti-CD3 x Anti-IGF1R Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD3 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-IGF1R scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget T cells to tumor cells. It is designed for the research of Melanoma; Colon cancer; Pancreas cancer; Prostate cancer; Kidney cancer therapy.
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