Home > Products > CD3 & P cadherin > Recombinant Anti-CD3 x Anti-P cadherin Bispecific Antibody (scFv4-Ig)

Recombinant Anti-CD3 x Anti-P cadherin Bispecific Antibody (scFv4-Ig)  (FVTIG-096)

Recombinant Anti-CD3 x Anti-P cadherin Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CD3 scFv is fused to the CH1 domain of a heavy chain and another anti-P cadherin scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Solid tumors therapy.

Specifications
Targets
CD3 & P cadherin
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Mouse
Target 2
P cadherin
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Solid tumors
Targets
Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
P cadherin
Gene ID
UniProt ID
Alternative Names
P cadherin; cadherin 3; CDH3; CDHP; HJMD; PCAD
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