Recombinant Anti-CD3 x Anti-PLAP Bispecific Antibody (scFv-Fc) (BSCFV-099)

Recombinant Anti-CD3 x Anti-PLAP Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-CD3 specificity or anti-PLAP specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget T cells to tumor cells. It is designed for the research of Ovarian cancer therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & PLAP

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Ovarian cancer

Targets

Target 1

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Target 2

PLAP

Gene ID

250

UniProt ID

P05187

Alternative Names

Alkaline Phosphatase; AP; basic phosphatase; PLAP; alkaline phosphatase, placental; ALPP; ALP; PLAP; PLAP-1

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD3 x Anti-PLAP Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-099)

Specifications

Targets

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