Home > Products > CD3 & PSCA > Recombinant Anti-CD3 x Anti-PSCA Bispecific Antibody (Triple Body)

Recombinant Anti-CD3 x Anti-PSCA Bispecific Antibody (Triple Body)  (TRIB-H277)

Recombinant Anti-CD3 x Anti-PSCA Bispecific Antibody (Triple Body) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-CD3 antibody are both extended with the scFv fragment from an anti-PSCA antibody. This BsAb can retarget T cells to tumor cells. It is designed for the research of Prostate cancer therapy.

Datasheet
Specifications
Targets
CD3 & PSCA
Type
Triple Body
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Human
Target 2
PSCA
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Prostate cancer
Targets
Target 1
CD3
Gene ID
916
UniProt ID
P07766
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
PSCA
Gene ID
8000
UniProt ID
D3DWI6
Alternative Names
PSCA; prostate stem cell antigen; PRO232

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