Name: Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (sdAb-Fc-sdAb)
SKU: HCAB-032
Rating: 5 (1 reviews)

Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (sdAb-Fc-sdAb, Tetravalent Heavy Chain-only Antibody, Tetravalent HCAb) is symmetric protein with two pairs of single domain antibodies (sdAb), from anti-CD3 and anti-PSMA antibodies, fused to the N-terminus and C-terminus of the Fc separately. This BsAb is bispecific, tetravelant, 2+2 antigen-binding valency. It can retarget T cells to tumor cells. It is designed for the research of Prostate cancer therapy.

Datasheet INQUIRY

Specifications

Targets

CD3 & PSMA

Type

sdAb-Fc-sdAb

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Prostate cancer

Host Animal 1

llama

Host Animal 2

llama

Targets

Target 1

CD3

Gene ID

2213

UniProt ID

P31994

Alternative Names

FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); FcγRIIB; CD32; FCG2; CD32B; FCGR2; IGFR2; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32)

Target 2

PSMA

Gene ID

974

UniProt ID

P40259

Alternative Names

CD79B; CD79b molecule, immunoglobulin-associated beta; Cluster of differentiation 79B; CD79b antigen; B29; IGB; AGM6; B-cell antigen receptor complex-associated protein beta chain; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta); immunoglobulin-associated CD79 beta

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD3 x Anti-PSMA Bispecific Antibody (sdAb-Fc-sdAb) (CAT#: HCAB-032)

Specifications

Targets

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