Recombinant Anti-CD3 x Anti-TROP2 Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can retarget T cells to tumor cells. It is designed for the research of Pancreatic cancer; Breast cancer; Gastrointestinal cancer; Cancers therapy.
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