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Anti-CD30 x Anti-CD64 Bispecific Antibody (IgG-IgG)  (BSIG-110)

Anti-CD30 x Anti-CD64 Bispecific Antibody (IgG-IgG) is designed to be generated by crosslinking two full length IgGs, anti-CD30 and anti-CD64 parental antibodies. A stable linkage is formed between the two antibodies. This BsAb can retarget neutrophilscells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.

Specifications

Targets
CD30 & CD64
Type
IgG-IgG
Species Reactivity
Human
Target 1
CD30
Host Animal 1
Mouse
Target 2
CD64
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL)

Targets

Target 1
CD30
Gene ID
UniProt ID
Alternative Names
TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

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