Home > Products > CD30 & CD64 > Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (scDiabody-CH3)

Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (scDiabody-CH3)  (SCDBC-110)

Recombinant Anti-CD30 x Anti-CD64 Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD30/anti-CD64 diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can retarget neutrophilscells to tumor cells. It is designed for the research of Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL) therapy.

Specifications

Targets
CD30 & CD64
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD30
Host Animal 1
Mouse
Target 2
CD64
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Neuroblastoma; Osteosarcoma; Hodgkin lymphoma; T cell lymphoma; Anaplastic large cell lymphoma (ALCL)

Targets

Target 1
CD30
Gene ID
UniProt ID
Alternative Names
TNFRSF8; tumor necrosis factor receptor superfamily, member 8; CD30; Ki-1; D1S166E; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

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