Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG-Fv) (BSGV-111)

Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-CD317 antibody variable domain is fused to the C terminal of an IgG of anti-CD16 antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Multiple myeloma (MM) therapy.

Datasheet INQUIRY

Specifications

Targets

CD317 & CD16

Type

IgG-Fv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple myeloma (MM)

Targets

Target 1

CD317

Gene ID

684

UniProt ID

A0A024R7H5

Alternative Names

CD317; TETHERIN; BST2; bone marrow stromal cell antigen 2; Cluster of differentiation 317

Target 2

CD16

Gene ID

2214

UniProt ID

M9MML0

Alternative Names

FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; low affinity immunoglobulin gamma Fc region receptor III-A; FcγRIII; FcgammaRIIIA; CD16a antigen; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; igG Fc receptor III-2; Fc gamma receptor III-A; Fc-gamma receptor IIIb (CD16); neutrophil-specific antigen NA; Fc-gamma receptor III-2 (CD 16); immunoglobulin G Fc receptor III; Fc fragment of IgG, low affinity III, receptor for (CD16)

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG-Fv) (CAT#: BSGV-111)

Specifications

Targets

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