Name: Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG(L)-scFv)
SKU: IGLFV-111
Rating: 5 (1 reviews)

Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-CD317 antibody are fused to the C terminus of an anti-CD16 IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can retarget NK cells to tumor cells. It is designed for the research of Multiple myeloma (MM) therapy.

Datasheet INQUIRY

Specifications

Targets

CD317 & CD16

Type

IgG-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple myeloma (MM)

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD317

Gene ID

684

UniProt ID

A0A024R7H5

Alternative Names

CD317; TETHERIN; BST2; bone marrow stromal cell antigen 2; Cluster of differentiation 317

Target 2

CD16

Gene ID

2214

UniProt ID

M9MML0

Alternative Names

FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; low affinity immunoglobulin gamma Fc region receptor III-A; FcγRIII; FcgammaRIIIA; CD16a antigen; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; igG Fc receptor III-2; Fc gamma receptor III-A; Fc-gamma receptor IIIb (CD16); neutrophil-specific antigen NA; Fc-gamma receptor III-2 (CD 16); immunoglobulin G Fc receptor III; Fc fragment of IgG, low affinity III, receptor for (CD16)

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-111)

Specifications

Targets

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