Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Miniantibody) (MNAB-111)

Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-CD317 antibody variable domain is linked to another scFv of an anti-CD16 antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Multiple myeloma (MM) therapy.

Datasheet INQUIRY

Specifications

Targets

CD317 & CD16

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple myeloma (MM)

Targets

Target 1

CD317

Gene ID

684

UniProt ID

A0A024R7H5

Alternative Names

CD317; TETHERIN; BST2; bone marrow stromal cell antigen 2; Cluster of differentiation 317

Target 2

CD16

Gene ID

2214

UniProt ID

M9MML0

Alternative Names

FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; low affinity immunoglobulin gamma Fc region receptor III-A; FcγRIII; FcgammaRIIIA; CD16a antigen; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; igG Fc receptor III-2; Fc gamma receptor III-A; Fc-gamma receptor IIIb (CD16); neutrophil-specific antigen NA; Fc-gamma receptor III-2 (CD 16); immunoglobulin G Fc receptor III; Fc fragment of IgG, low affinity III, receptor for (CD16)

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD317 x Anti-CD16 Bispecific Antibody (Miniantibody) (CAT#: MNAB-111)

Specifications

Targets

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