Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Miniantibody) (MNAB-112)

Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (Miniantibody) is a fusion protein of two scFv fragments combined with distinct specificity. One scFv of an anti-CD32B antibody variable domain is linked to another scFv of an anti-CD79B antibody variable domain by a flexible hinge region. This BsAb format has the decreased size and better penetration than conventional IgGs in the clinical diagnostics and potentially therapy. This BsAb can regulate B-cell modulation. It is designed for the research of Immune diseases therapy.

Datasheet

Specifications

Targets

CD32B & CD79B

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Target 1

CD32B

Host Animal 1

Mouse

Target 2

CD79B

Host Animal 2

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

Immune diseases

Targets

Target 1

CD32B

Gene ID

2213

UniProt ID

P31994

Alternative Names

FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); FcγRIIB; CD32; FCG2; CD32B; FCGR2; IGFR2; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32)

Target 2

CD79B

Gene ID

974

UniProt ID

P40259

Alternative Names

CD79B; CD79b molecule, immunoglobulin-associated beta; Cluster of differentiation 79B; CD79b antigen; B29; IGB; AGM6; B-cell antigen receptor complex-associated protein beta chain; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta); immunoglobulin-associated CD79 beta

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