Recombinant Anti-CD32B x Anti-CD79B Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD32B scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CD79B scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can regulate B-cell modulation. It is designed for the research of Immune diseases therapy.