Recombinant Human Anti-CD32B x Human Anti-malaria antigen Bispecific Antibody (scFv-Fc-scFv) (BSTF-H289)

Recombinant Anti-CD32B x Anti-malaria antigen Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CD32B scFv is fused to the N-terminus of Fc via a hinge region while another anti-malaria antigen scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of Malaria therapy.

Datasheet INQUIRY

Specifications

Targets

CD32B & malaria antigen

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Malaria

Targets

Target 1

CD32B

Gene ID

2213

UniProt ID

P31994

Alternative Names

FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); FcγRIIB; CD32; FCG2; CD32B; FCGR2; IGFR2; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32)

Target 2

malaria antigen

Alternative Names

malaria antigen; parasitic protozoans

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD32B x Human Anti-malaria antigen Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-H289)

Specifications

Targets

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