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Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Minibody) (CAT#: MiniB-114)
Recombinant Anti-CD33 x Anti-CD16 Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD33 scFv fused to N-terminus of Knob-CH3 domain and the anti-CD16 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Acute myeloid leukemia (AML); Ulcerative Colitis (UC); Myelodysplastic syndromes (MDS); Gastric cancer therapy.
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