Name: Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Minibody)
SKU: MiniB-115
Rating: 5 (1 reviews)

Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD33 scFv fused to N-terminus of Knob-CH3 domain and the anti-CD64 scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Acute myeloid leukemia (AML); Ulcerative Colitis (UC); Myelodysplastic syndromes (MDS); Gastric cancer therapy.

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Specifications

Targets

CD33 & CD64

Type

Minibody

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Acute myeloid leukemia (AML); Ulcerative Colitis (UC); Myelodysplastic syndromes (MDS); Gastric cancer

Targets

Target 1

CD33

Gene ID

945

UniProt ID

P20138

Alternative Names

CD33; CD33 molecule; Cluster of differentiation 33; p67; SIGLEC3; SIGLEC-3; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3

Target 2

CD64

Gene ID

2209

UniProt ID

P12314

Alternative Names

FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD33 x Anti-CD64 Bispecific Antibody (Minibody) (CAT#: MiniB-115)

Specifications

Targets

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