Recombinant Human Anti-CD33 x Human Anti-DENV Bispecific Antibody (Diabody-CH3) (BSDBC-H292)

Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-CD33 and anti-DENV antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb is designed for the research of antibody-dependent enhancement (ADE) and dengue virus infection.

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Specifications

Targets

CD33 & DENV

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS

Related Disease

Dengue virus infection

Targets

Target 1

CD33

Gene ID

945

UniProt ID

P20138

Alternative Names

CD33; CD33 molecule; Cluster of differentiation 33; p67; SIGLEC3; SIGLEC-3; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3

Target 2

DENV

Alternative Names

dengue virus; DENV; dengue fever; Flavivirus

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD33 x Human Anti-DENV Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-H292)

Specifications

Targets

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