Home > Products > CD33 & DENV > Recombinant Human Anti-CD33 x Human Anti-DENV Bispecific Antibody (Diabody-Fc)

Recombinant Human Anti-CD33 x Human Anti-DENV Bispecific Antibody (Diabody-Fc)  (BSDBF-H292)

Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-CD33 and anti-DENV antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb is designed for the research of antibody-dependent enhancement (ADE) and dengue virus infection.

Specifications

Targets
CD33 & DENV
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD33
Host Animal 1
Human
Target 2
DENV
Host Animal 2
Human
Application
FuncS
Related Disease
Dengue virus infection

Targets

Target 1
CD33
Gene ID
UniProt ID
Alternative Names
CD33; CD33 molecule; Cluster of differentiation 33; p67; SIGLEC3; SIGLEC-3; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3
Target 2
DENV
Alternative Names
dengue virus; DENV; dengue fever; Flavivirus

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