Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (scFv-Fc-scFv) (BSTF-116)

Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CD33 scFv is fused to the N-terminus of Fc via a hinge region while another anti-DENV scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb is designed for the research of antibody-dependent enhancement (ADE) and dengue virus infection.

Datasheet INQUIRY

Specifications

Targets

CD33 & DENV

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS

Related Disease

Dengue virus infection

Targets

Target 1

CD33

Gene ID

945

UniProt ID

P20138

Alternative Names

CD33; CD33 molecule; Cluster of differentiation 33; p67; SIGLEC3; SIGLEC-3; myeloid cell surface antigen CD33; gp67; CD33 antigen (gp67); sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3

Target 2

DENV

Alternative Names

dengue virus; DENV; dengue fever; Flavivirus

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD33 x Anti-DENV Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-116)

Specifications

Targets

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