Home > Products > CD37 & CD64 > Recombinant Anti-CD37 x Anti-CD64 Bispecific Antibody (Fab-Fv)

Recombinant Anti-CD37 x Anti-CD64 Bispecific Antibody (Fab-Fv)  (FABFV-117)

Recombinant Anti-CD37 x Anti-CD64 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-CD37 antibody are fused with the VL and VH domains of an anti-CD64 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL) therapy.

Specifications
Targets
CD37 & CD64
Type
Fab-Fv
Species Reactivity
Human
Target 1
CD37
Host Animal 1
Mouse
Target 2
CD64
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL)
Targets
Target 1
CD37
Gene ID
UniProt ID
Alternative Names
CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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INQUIRY
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Fax: 1-631-207-8356
Email:

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Tel: 44-207-097-1828
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