Home > Products > CD37 & CD64 > Recombinant Anti-CD37 x Anti-CD64 Bispecific Antibody (Single-chain Diabody)

Recombinant Anti-CD37 x Anti-CD64 Bispecific Antibody (Single-chain Diabody)  (SCDB-117)

Recombinant Anti-CD37 x Anti-CD64 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can retarget neutrophils cells to tumor cells. It is designed for the research of Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL) therapy.

Specifications
Targets
CD37 & CD64
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
CD37
Host Animal 1
Mouse
Target 2
CD64
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL)
Targets
Target 1
CD37
Gene ID
UniProt ID
Alternative Names
CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI

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