Recombinant Anti-CD37 x Anti-Saporin Bispecific Antibody (scDiabody-CH3) (SCDBC-118)

Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD37/anti-saporin diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL) therapy.

Datasheet INQUIRY

Specifications

Targets

CD37 & Saporin

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Pretargeting system for immunotoxin delivery

Related Disease

Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL)

Targets

Target 1

CD37

Gene ID

951

UniProt ID

P11049

Alternative Names

CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37

Target 2

Saporin

Alternative Names

Saporin; Ribosome inactivating protein; RIP

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD37 x Anti-Saporin Bispecific Antibody (scDiabody-CH3) (CAT#: SCDBC-118)

Specifications

Targets

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