Name: Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scFv-Fc-scFv)
SKU: BSTF-118
Rating: 5 (1 reviews)

Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CD37 scFv is fused to the N-terminus of Fc via a hinge region while another anti-saporin scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL) therapy.

Datasheet INQUIRY

Specifications

Targets

CD37 & saporin

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Pretargeting system for immunotoxin delivery

Related Disease

Non-Hodgkin's lymphoma (NHL); Diffuse large B cell lymphoma (DLBCL); Chronic lymphocytic leukemia (CLL)

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD37

Gene ID

951

UniProt ID

P11049

Alternative Names

CD37; CD37 molecule; GP52-40; TSPAN26; leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37

Target 2

saporin

Alternative Names

Saporin; Ribosome inactivating protein; RIP

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD37 x Anti-saporin Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-118)

Specifications

Targets

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