Home > Products > CD38 & CD59 > Recombinant Human Anti-CD38 x Human Anti-CD59 Bispecific Antibody (IgG-Fv)

Recombinant Human Anti-CD38 x Human Anti-CD59 Bispecific Antibody (IgG-Fv)  (BSGV-H294)

Recombinant Anti-CD38 x Anti-CD59 Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-CD38 antibody variable domain is fused to the C terminal of an IgG of anti-CD59 antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can recruit complement to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.

Specifications

Targets
CD38 & CD59
Type
IgG-Fv
Species Reactivity
Human
Target 1
CD38
Host Animal 1
Mouse
Target 2
CD59
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Multiple myeloma (MM); Hematologic malignancies

Targets

Target 1
CD38
Gene ID
UniProt ID
Alternative Names
CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolase
Target 2
CD59
Gene ID
UniProt ID
Alternative Names
CD59; CD59 molecule, complement regulatory protein; 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20; CD59 glycoprotein; protectin; 1F5 antigen; MEM43 antigen; Ly-6-like protein; T cell-activating protein; human leukocyte antigen MIC11; lymphocytic antigen CD59/MEM43; 20 kDa homologous restriction factor; membrane inhibitor of reactive lysis; membrane attack complex inhibition factor; membrane attack complex (MAC) inhibition factor; surface anitgen recognized by monoclonal antibody 16.3A5; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)

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