Home > Products > CD38 & CD59 > Recombinant Anti-CD38 x Anti-CD59 Bispecific Antibody (Single-chain Diabody)

Recombinant Anti-CD38 x Anti-CD59 Bispecific Antibody (Single-chain Diabody)  (SCDB-H292)

Recombinant Anti-CD38 x Anti-CD59 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can recruit complement to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.

Datasheet
Specifications
Targets
CD38 & CD59
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
CD38
Host Animal 1
Human
Target 2
CD59
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Multiple myeloma (MM); Hematologic malignancies
Targets
Target 1
CD38
Gene ID
952
UniProt ID
P28907
Alternative Names
CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolase
Target 2
CD59
Gene ID
966
UniProt ID
P13987
Alternative Names
CD59; CD59 molecule, complement regulatory protein; 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20; CD59 glycoprotein; protectin; 1F5 antigen; MEM43 antigen; Ly-6-like protein; T cell-activating protein; human leukocyte antigen MIC11; lymphocytic antigen CD59/MEM43; 20 kDa homologous restriction factor; membrane inhibitor of reactive lysis; membrane attack complex inhibition factor; membrane attack complex (MAC) inhibition factor; surface anitgen recognized by monoclonal antibody 16.3A5; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
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