Recombinant Anti-CD38 x Anti-CD59 Bispecific Antibody (Tandem Fab) (BSFAB-H292)

Recombinant Anti-CD38 x Anti-CD59 Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-CD38 and anti-CD59 parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can recruit complement to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.

Datasheet

Specifications

Targets

CD38 & CD59

Type

Tandem Fab

Species Reactivity

Human

Target 1

CD38

Host Animal 1

Human

Target 2

CD59

Host Animal 2

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple myeloma (MM); Hematologic malignancies

Targets

Target 1

CD38

Gene ID

952

UniProt ID

P28907

Alternative Names

CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolase

Target 2

CD59

Gene ID

966

UniProt ID

P13987

Alternative Names

CD59; CD59 molecule, complement regulatory protein; 1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20; CD59 glycoprotein; protectin; 1F5 antigen; MEM43 antigen; Ly-6-like protein; T cell-activating protein; human leukocyte antigen MIC11; lymphocytic antigen CD59/MEM43; 20 kDa homologous restriction factor; membrane inhibitor of reactive lysis; membrane attack complex inhibition factor; membrane attack complex (MAC) inhibition factor; surface anitgen recognized by monoclonal antibody 16.3A5; CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY

Online Inquiry

USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Europe
Heidenkampsweg 58, 20097 Hamburg, Germany
Tel: 44-207-097-1828
Email: