Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Diabody-CH3) (BSDBC-120)

Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-CD38 and anti-saporin antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.

Datasheet INQUIRY

Specifications

Targets

CD38 & saporin

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Pretargeting system for immunotoxin delivery

Related Disease

Multiple myeloma (MM); Hematologic malignancies

Targets

Target 1

CD38

Gene ID

951

UniProt ID

P11049

Alternative Names

CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolase

Target 2

saporin

Alternative Names

Saporin; Ribosome inactivating protein; RIP

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-120)

Specifications

Targets

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