Home > Products > CD38 & saporin > Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Diabody-CH3)

Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Diabody-CH3)  (BSDBC-120)

Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-CD38 and anti-saporin antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.

Specifications
Targets
CD38 & saporin
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Target 1
CD38
Host Animal 1
Mouse
Target 2
saporin
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for immunotoxin delivery
Related Disease
Multiple myeloma (MM); Hematologic malignancies
Targets
Target 1
CD38
Gene ID
UniProt ID
Alternative Names
CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolase
Target 2
saporin
Alternative Names
Saporin; Ribosome inactivating protein; RIP
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