Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (Minibody) is designed to be expressed as the anti-CD38 scFv fused to N-terminus of Knob-CH3 domain and the anti-saporin scFv to the Hole-CH3 domain, or vice versa. The CH3 domains are further stabilized by C-terminal disulfide bonds. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.
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