Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scDiabody-Fc) is a fusion protein of two scDiabodies with an Fc region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-CD38/anti-saporin diabody. The scDiabody with two specificities is further fused to the Fc domain to form BsAb with 2+2 antigen-binding valency. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.
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