Home > Products > CD38 & saporin > Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scFv-CH3)

Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scFv-CH3)  (BSFC-120)

Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD38 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-saporin scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.

Specifications
Targets
CD38 & saporin
Type
scFv-CH3
Species Reactivity
Human
Target 1
CD38
Host Animal 1
Mouse
Target 2
saporin
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for immunotoxin delivery
Related Disease
Multiple myeloma (MM); Hematologic malignancies
Targets
Target 1
CD38
Gene ID
UniProt ID
Alternative Names
CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolase
Target 2
saporin
Alternative Names
Saporin; Ribosome inactivating protein; RIP
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