Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scFv-Fc-scFv) (BSTF-120)

Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scFv-Fc-scFv) is designed to be expressed as one chain, then assembled to a homodimer of bivalent scFv fragments and the Fc region of IgG. The anti-CD38 scFv is fused to the N-terminus of Fc via a hinge region while another anti-saporin scFv is linked to the C-terminus of Fc. This scFv-Fc-scFv format has 2+2 antigen-binding valency by employing different scFv fragments. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.

Datasheet INQUIRY

Specifications

Targets

CD38 & saporin

Type

scFv-Fc-scFv

Species Reactivity

Human

Application

FuncS; Pretargeting system for immunotoxin delivery

Related Disease

Multiple myeloma (MM); Hematologic malignancies

Targets

Target 1

CD38

Gene ID

951

UniProt ID

P11049

Alternative Names

CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolase

Target 2

saporin

Alternative Names

Saporin; Ribosome inactivating protein; RIP

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scFv-Fc-scFv) (CAT#: BSTF-120)

Specifications

Targets

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