Home > Products > CD38 & saporin > Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scFv-IgG)

Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scFv-IgG)  (BSSG-120)

Recombinant Anti-CD38 x Anti-saporin Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD38 antibody variable domain are respectively connected to the N terminus of the anti-saporin IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can be used in pretargeting system and deliver immunotoxin to tumor cells. It is designed for the research of Multiple myeloma (MM); Hematologic malignancies therapy.

Specifications
Targets
CD38 & saporin
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD38
Host Animal 1
Mouse
Target 2
saporin
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for immunotoxin delivery
Related Disease
Multiple myeloma (MM); Hematologic malignancies
Targets
Target 1
CD38
Gene ID
UniProt ID
Alternative Names
CD38; Cluster of differentiation 38; CD38 molecule; ADPRC1; ADPRC 1; Cyclic ADP ribose hydrolase
Target 2
saporin
Alternative Names
Saporin; Ribosome inactivating protein; RIP
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